Biomarker discovery       

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Biomarker discovery - overview


To make diagnostics truly personalized — assign each patient to a disease subtype, determine the aggressiveness of the disease, suggest individualized treatment options — modern precision medicine requires biomarkers.

Advances in high-throughput data generation have dramatically expanded the search space for biomarker discovery, making the selection of an optimal biomarker signature from large and noisy datasets challenging. Thus, the task of selecting a biomarker signature — a small number of predictors able to predict the response — has become an important task in omics research.