Bio-Nanosensors Research Group Publications



2016

Directed surface functionalization on selected surface areas of topographical features with nanometer resolution, US Patent 9,255,321 issued
S. Harrer, J. Baldauf, C. Schieber

Directed surface functionalization on selected surface areas of topographical features with nanometer resolution, US Patent US 9,297,062 issued [also see US 9,255,321]
S. Harrer, C. Schieber, J. Baldauf

Nanofluidic sensor comprising spatially separated functional sensing components, US Patent 9,303,310 issued
S. Harrer, C. Schieber, J. Baldauf


2015

Detection of translocation events using graphene-based nanopore assemblies, US Patent Application US 20150377380. A1
S. Harrer, J. Baldauf, M. Downton, N. Gunn, S. Kannam, C. Schieber, J. Wagner

Micro-droplet fluidic cell for fast ionic current detection using nanopores, US Patent Application US 20150209779
S. Harrer, Y. Kwark, S. Polonsky

Measuring life: sensors and analytics for precision medicine (Plenary Paper)
S. Harrer
Proc. SPIE 9518, Bio-MEMS and Medical Microdevices II, 951802, 2015.

Nanofluidic sensor comprising spatially separated functional sensing components, US Patent Application US 20150104354 [cont. US 20150104587]
S. Harrer, C. Schieber, J. Baldauf

Directed surface functionalization on selected surface areas of topographical features with nanometer resolution, US Patent Application US 20150104586
S. Harrer, C. Schieber, J. Baldauf

Label-free screening of single biomolecules through resistive pulse sensing technology for precision medicine applications (invited, special issue 'DNA Sequencing')
S. Harrer, S. C. Kim, C. Schieber, S. Kannam, N. Gunn, S. Moore, D. Scott, R. Bathgate, S. Skafidas, J. M. Wagner
Nanotechnology 26(18), 182502, 2015

Nano-fluidic field effective device to control DNA transport through the same, US Patent 8,940,148 B2 issued
S. Harrer, A. Afzali-Ardakani, B. Luan, G. J. Martyna, D. M. Newns, H. Peng, S. Polonsky, S. Rossnagel, G. Stolovitzky

DNA sequencing using multiple metal layer structure with different organic coatings forming different transient bondings to DNA, US Patent 8,986,524 issued
S. Harrer, A. Afzali-Ardakani, B. Luan, H. Peng, S. M. Rossnagel, A. K. Royyuru, G. Stolovitzky, P. S. Waggoner


2014

Feedback control of dimensions in nanopore and nanofluidic devices, UK Patent 2,499,161 issued
S. Harrer, S. M. Rossnagel, P. S. Waggoner

Nano-Pipet Fabrication, US Patent Application US 20140103582A1
S. Harrer, J. A. Ott, S. Polonsky

Nano-Pipet Fabrication, US Patent Application US 20140105794A1, [cont. 20140103582A1]
S. Harrer, J. A. Ott, S. Polonsky

Charged Entities as locomotive to control motion of polymers through a nanochannel,[also see US 8,641,879], US Patent 8,691,067 issued
S. Harrer, B. Luan, G. J. Martyna, H. Peng, S. Polonsky, S. M. Rossnagel, A. K. Royyuru, G. A. Stolovitzky, G. F. Walker

Regulating the transport of DNA through biofriendly nanochannels in a thin solid membrane
Deqiang Wang, Stefan Harrer, Binquan Luan, Gustavo Stolovitzky, Hongbo Peng, Ali Afzali-Ardakani
Scientific reports4, Nature Publishing Group, 2014

Crossed slit structure for nanopores (device patent), US Patent Application 20140004300A1
S. Harrer, J. Bai, S. Polonsky, S. M. Rossnagel

Methods of directed self-assembly and layered structures formed therefrom, US Patent 8,623,458, UK Patent 2,485,941, and China Patent ZL201080057340.8 issued
J. Cheng, M. E. Colburn, S. Harrer, W. D. Hinsberg, S. J. Holmes, H.-C. Kim, D. P. Sanders

Semiconductor devices having nanochannels confined by nanometer-spaced electrodes, [also see US 8,558,326], US Patent 8,691,608 issued
S. Harrer, S. Polonsky, M. B. Ketchen, J. A. Ott

Charged Entities as locomotive to control motion of polymers through a nanochannel, US Patent 8,641,879 and UK Patent 2,507,706 issued
S. Harrer, B. Luan, G. J. Martyna, H. Peng, S. Polonsky, S. M. Rossnagel, A. K. Royyuru, G. A. Stolovitzky, G. F. Walker

DNA sequencing using multiple metal layer structure with organic coatings forming transient bonding to DNA bases, US Patent 8,764,968 issued
A. Afzali-Ardakani, S. Harrer, B. Luan, G. J. Martyna, H. Peng. S. M. Rossnagel, G. Stolovitzky, P. S. Waggoner, G. F. Walker

Modifying proteins (GPCR), ligands, and nanopore surfaces to allow the detection of binding-induced molecular changes of protein-ligand complexes with nanochannel translocation, US Patent Application US20140179540A1
S. Harrer, M. Downton, N. Gunn, P. Rogers, J. Wagner, R. Bathgate, D. Scott, S. Skafidas

Sensing of protein molecules through nanopores: a molecular dynamics study
Sridhar Kumar Kannam, Sung Cheol Kim, Priscilla R Rogers, Natalie Gunn, John Wagner, Stefan Harrer, Matthew T Downton
Nanotechnology 25(15), 155502, IOP Publishing, 2014

Modifying single proteins (GPCR), ligands, and nanopore surfaces to create binding-induced molecular changes of protein-ligand complexes detected in nanochannel translocation, US Patent 8,835,362 issued
S. Harrer, M. Downton, N. Gunn, P. Rogers, J. Wagner, R. Bathgate, D. Scott, S. Skafidas

Geometric dependence of the conductance drop in a nanopore due to a particle
Sung Cheol Kim, Sridhar Kumar Kannam, Stefan Harrer, Matthew T Downton, Stephen Moore, John M Wagner
Physical Review E 89(4), 042702, American Physical Society, 2014

Crossed slit structure for nanopores (method patent), US Patent Application 20140001149A1
S. Harrer, J. Bai, S. Polonsky, S. M. Rossnagel


2013

Nanosensors for next generation drug screening
Sridhar K Kannam, Matthew T Downton, Natalie Gunn, Sung Cheol Kim, Priscilla R Rogers, Christine Schieber, Julia S Baldauf, John M Wagner, Daniel Scott, Ross Bathgate, others
SPIE Micro+ Nano Materials, Devices, and Applications, pp. 89230I--89230I, 2013

Forming an electrode having reduced corrosion and water decomposition on surface using a custom oxide layer, US Patent 8,598,081 issued
A. Afzali-Ardakani, S. Ahmed, H. Deligianni, D. L. Goldfarb, S. Harrer, H. Peng, S. Polonsky, S. Rossnagel, X. Shao, G. A. Stolovitzky

Functionally switchable self-assembled coating compound for controlling translocation of molecule through nanopores (device patent), US Patent Application 20130264219
S. Harrer, A. Afzali-Ardakani, B. Luan, H. Peng, G. A. Stolovitzky, D. Wang

Method of fabricating dual damascene structures using a multilevel multiple exposure patterning scheme, US Patent 8,536,031 issued
J. C. Arnold, K.-J. Chen, M. E. Colburn, D. L. Goldfarb, S. Harrer, S. J. Holmes, P. Varanasi

Semiconductor devices having nanochannels confined by nanometer-spaced electrodes, US Patent 8,558,326 issued
S. Harrer, S. Polonsky, M. B. Ketchen, J. A. Ott

Forming an electrode having reduced corrosion and water decomposition on surface using an organic protective layer, US Patent 8,354,336 issued
S. Harrer, A. Afzali-Ardakani, S. Ahmed, H. Deligianni, D. L. Goldfarb, H. Peng, S. Polonsky, S. Rossnagel, X. Shao, G. A. Stolovitzky

Functionally switchable self-assembled coating compound for controlling translocation of molecule through nanopores, US Patent Application 20130263946
S. Harrer, A. Afzali-Ardakani, B. Luan, H. Peng, G. A. Stolovitzky, D. Wang


2012

DNA-translocation through a solid-state nanopore coated with a functionally switchable self-assembled monolayer
S. Harrer, D. Wang, B. Luan, G. A. Stolovitzky, H. Peng, A. Afzali-Ardakani
Proc. 222nd ECS PRiME Conference 2012

Dynamics of DNA translocation in a solid-state nanopore immersed in aqueous glycerol
B. Luan, D. Wang, R. Zhou, S. Harrer, H. Peng, G. Stolovitzky
Nanotechnology 23(45), 455102, IOP Publishing, 2012

DNA motion control based on nanopore with organic coating forming transient bonding to DNA, US Patent Application US 2012/0193235A1
A. Afzali-Ardakani, S. Harrer, B. Luan, G. J. Martyna, H. Peng, S. M. Rossnagel, A. K. Royyuru, G. Stolovitzky, P. S. Waggoner

Feedback control of dimensions in nanopore and nanofluidic devices, US Patent Application 20120103821A1 and WO Patent Application 2012059251
S. Harrer, S. M. Rossnagel, P. S. Waggoner