Noel Faux  Noel Faux photo       

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Research Staff Member
Australian Research Laboratory, Melbourne
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2017

CuII(atsm) improves the neurological phenotype and survival of SOD1G93A mice and selectively increases enzymatically active SOD1 in the spinal cord.
Hilton JB, Mercer SW, Lim NKH, Faux NG, Buncic G, Beckman JS, Roberts BR, Donnelly PS, White AR, Crouch PJ.
Science ReportsIn press, accepted 9 Jan, 2017
Abstract

Association of Cerebrospinal Fluid Ferritin Level With Preclinical Cognitive Decline in APOE-4 Carriers
Ayton S; Faux NG, Bush AI
JAMA Neurol. 74(1), 122-125, 2017
Abstract


2016

Predicting Alzheimer' s disease from a blood-based biomarker profile: a 54 month follow up
Burnham SC, Rowe CC, Baker D, Bush AI, Doecke JD, Faux NG, Laws SM, Martins RN, Maruff P, Macaulay S, Rainey-Smith S, Savage G, Ames D, Masters CL, Wilson W, Villemagne VL
Neurology 87(11), 1093-1101, 2016
Abstract

Lead and manganese levels in serum and erythrocytes in Alzheimer's disease and mild cognitive impairment: results from the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing
Dominic J. Hare, Noel G. Faux, Blaine R. Roberts, Irene Volitakis, Ralph N. Martins and Ashley I. Bush
Metallomics, 2016
Abstract


2015

Peripheral alpha-Defensins 1 and 2 are Elevated in Alzheimer's Disease
AD Watt, KA Perez, C-S Ang, P O'Donnell, A Rembach, KK Pertile, RL Rumble, BO Trounson, CJ Fowler, NG Faux, CL Masters, VL Villemagne, KJ Barnham
JOURNAL OF ALZHEIMERS DISEASE44, 1131--1143, IOS PRESS, 2015

Decreased Plasma Iron in Alzheimer's Disease Is Due to Transferrin Desatu ration
DJ Hare, JD Doecke, NG Faux, A Rembach, I Volitakis, CJ Fowler, R Grimm, PA Doble, RA Cherny, CL Masters, AI Bush, BR Roberts
ACS CHEMICAL NEUROSCIENCE6, 398--402, AMER CHEMICAL SOC, 2015

Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE
S Ayton, NG Faux, AI Bush
NATURE COMMUNICATIONS 6(ARTN 6760), NATURE PUBLISHING GROUP, 2015


2014

A blood-based predictor for neocortical Aβ burden in Alzheimer's disease: results from the AIBL study.
SC Burnham, NG Faux, W Wilson, SM Laws, D Ames, J Bedo, AI Bush, JD Doecke, KA Ellis, R Head, G Jones, H Kiiveri, RN Martins, A Rembach, CC Rowe, O Salvado, SL Macaulay, CL Masters, VL Villemagne, Alzheimer’s Disease Neuroimaging Initiative, Biomarkers
Mol Psychiatry19, 519--526, 2014
Abstract

Altered transition metal homeostasis in Niemann-Pick disease, type C1
YH Hung, NG Faux, I Volitakis, G Ganio, AI Bush, DW Killilea, N Yanjanin, FD Porter, S Firnkes, DS Ory, M Walterfang, C Hastings
Metallomics6, 542--553, 2014
Abstract

Among vitamin B12 deficient older people, high folate levels are associated with worse cognitive function: Combined data from three cohorts
EM Moore, D Ames, AG Mander, RP Carne, H Brodaty, MC Woodward, K Boundy, KA Ellis, AI Bush, NG Faux, RN Martins, CL Masters, CC Rowe, C Szoeke, DA Watters
Journal of Alzheimer's Disease39, 661--668, 2014
Abstract

Response to comment on moore et Al. Increased risk of cognitive impairment in patients with diabetes is associated with metformin
E MOORE, AG Mander, DJ Ames, MA Kotowicz, RP Carne, H Brodaty, M Woodward, KA Ellis, AI Bush, NG Faux, DA Watters
Diabetes Care 37(e151), 2014

Changes in plasma amyloid beta in a longitudinal study of aging and Alzheimer's disease.
A Rembach, NG Faux, AD Watt, KK Pertile, RL Rumble, BO Trounson, CJ Fowler, BR Roberts, KA Perez, QX Li, SM Laws, K Taddei, S Rainey-Smith, JS Robertson, M Vandijck, H Vanderstichele, KJ Barnham, KA Ellis, C Szoeke, L Macaulay, CC Rowe, VL Villemagne, D A
Alzheimers Dement10, 53--61, 2014
Abstract

An anemia of Alzheimer's disease
NG Faux, A Rembach, J Wiley, KA Ellis, D Ames, CJ Fowler, RN Martins, KK Pertile, RL Rumble, B Trounson, CL Masters, AI Bush
MOLECULAR PSYCHIATRY19, 1227--1234, NATURE PUBLISHING GROUP, 2014


2013

Longitudinal analysis of serum copper and ceruloplasmin in Alzheimer's disease.
A Rembach, JD Doecke, BR Roberts, AD Watt, NG Faux, I Volitakis, KK Pertile, RL Rumble, BO Trounson, CJ Fowler, W Wilson, KA Ellis, RN Martins, CC Rowe, VL Villemagne, D Ames, CL Masters, AIBL research group, AI Bush
J Alzheimers Dis34, 171--182, 2013
Abstract

Increased Risk of Cognitive Impairment in Patients With Diabetes Is Associated With Metformin
EM Moore, AG Mander, D Ames, MA Kotowicz, RP Carne, H Brodaty, M Woodward, K Boundy, KA Ellis, AI Bush, NG Faux, R Martins, C Szoeke, C Rowe, DA Watters
DIABETES CARE36, 2981--2987, AMER DIABETES ASSOC, 2013


2012

Blood-Based Protein Biomarkers for Diagnosis of Alzheimer Disease
JD Doecke, SM Laws, NG Faux, W Wilson, SC Burnham, C Lam, A Mondal, J Bedo, AI Bush, B Brown, K De Ruyck, KA Ellis, C Fowler, VB Gupta, R Head, L Macaulay, K Pertile, C Rowe, A Rembach, M Rodrigues, R Rumble, C Szoeke, K Taddei, T Taddei, B Trounson, DJ A
Archives of Neurology69, 1318--1325, 2012

Associations between gonadotropins, testosterone and β amyloid in men at risk of Alzheimer's disease
G Verdile, SM Laws, VB Gupta, K Taddei, RN Martins, D Henley, D Ames, KA Ellis, AI Bush, CL Masters, NG Faux, KE Pike, Q-X Li, VL Villemagne, CC Rowe, C Szoeke
Molecular Psychiatry, 2012
Abstract

Single amino acid and trinucleotide repeats function and evolution
N Faux
Advances in Experimental Medicine and Biology769, 26--40, Springer New York LLC, 2012
Abstract


2011

Increasing the Predictive Accuracy of Amyloid-beta Blood-Borne Biomarkers in Alzheimer's Disease
A WATT, K Perez, N Faux, K Pike, C Rowe, P Bourgeat, O Salvado, CL Masters, V Villemagne, K Barnham
Journal of Alzheimer's Disease24, 47--59, 2011

Effects of anticholinergic drugs on cognitive function in older Australians: results from the AIBL study
G Sittironnarit, DJ Ames, AI Bush, NG Faux, L Flicker, J Foster, S Hilmer, NT Lautenschlager, PT Maruff, CL Masters, RN Martins, C Rowe, C Szoeke, KA Ellis
Dementia and Geriatric Cognitive Disorders31, 173--178, 2011

Homocysteine, Vitamin B12, and Folic Acid Levels in Alzheimer's Disease, Mild Cognitive Impairment, and Healthy Elderly: Baseline Characteristics in Subjects of the Australian Imaging Biomarker Lifestyle Study
NG Faux, KA Ellis, L Porter, CJ Fowler, SM Laws, RN Martins, KK Pertile, A Rembach, C Rowe, RL Rumble, C Szoeke, K Taddei, BO Trounson, VL Villemagne, V Ward, DJ Ames, CL Masters, AI Bush
Journal of Alzheimer's Disease27, 909--922, 2011


2010

Blood-Borne Amyloid-\\β Dimer Correlates with Clinical Markers of Alzheimer's Disease
V VILLEMAGNE, K PEREZ, K PIKE, WM KOK, C ROWE, A WHITE, Bourgeat, Salvado, J BEDO, C HUTTON, N FAUX, C MASTERS, K BARNHAM
Journal of Neuroscience30, 6315--6322, 2010

Plasma amyloid-beta as a biomarker in Alzheimer's disease:the AIBL study of aging
K Lui, M Laws, LQ Qiao-Xin, VLV Villemagne, D AMES, Brown, AIB Bush, De Ruyck, Dromey, KAE Ellis, NGF Faux, Foster, CJ Fowler, Gupta, PLH Hudson, KML Laughton, CLM Masters, KK Pertile, AR Rembach, Rimajova, Rodrigues, C Rowe, RL Rumble, C Szoeke, Taddei,
Journal of Alzheimer's Disease20, 1233--1242, 2010

Larger temporal volume in elderly with high versus low beta-amyloid deposition
G Chetelat, V VILLEMAGNE, KE Pike, J Baron, P Bourgeat, G Jones, N FAUX, K ELLIS, O Salvado, C Szoeke, R Martins, D Ames, C MASTERS, C ROWE
Brain133, 3349--3358, 2010

PBT2 Rapidly Improves Cognition in Alzheimer's Disease: Additional Phase II Analyses
N FAUX, C Ritchie, A Gunn, A REMBACH, A Tsatsanis, J Bedo, J Harrison, L Lannfelt, K Blennow, H Zetterberg, M Ingelsson, CL Masters, R Tanzi, J Cummings, C Herd, A BUSH
Journal of Alzheimer's Disease20, 509--516, 2010


2007

GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop
G Fenalti, RHP Law, AM Buckle, C Langendorf, K Tuck, CJ Rosado, NG Faux, K Mahmood, CS Hampe, JP Banga, M Wilce, J Schmidberger, J Rossjohn, O El-Kabbani, RN Pike, AI Smith, IR Mackay, MJ Rowley, JC Whisstock
NATURE STRUCTURAL \\& MOLECULAR BIOLOGY14, 280--286, NATURE PUBLISHING GROUP, 2007

RCPdb: An evolutionary classification and codon usage database for repeat-containing proteins.
NG Faux, GA Huttley, K Mahmood, GI Webb, MG de la Banda, JC Whisstock
Genome Res17, 1118--1127, 2007
Abstract

Protein Folding Database (PFD 2.0): an online environment for the International Foldeomics Consortium.
KF Fulton, MA Bate, NG Faux, K Mahmood, C Betts, AM Buckle
Nucleic Acids Res35, D304--D307, 2007
Abstract


2006

Managing and mining protein crystallization data
AA Amin, NG Faux, G Fenalti, G Williams, A Bernadou, B Daglish, K Keefe, S Middleton, J Rae, K Tetis, RHP Law, KF Fulton, J Rossjohn, JC Whisstock, AM Buckle
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS62, 4--7, WILEY-LISS, 2006


2005

Functional insights from the distribution and role of homopeptide repeat-containing proteins.
NG Faux, SP Bottomley, AM Lesk, JA Irving, JR Morrison, MG de la Banda, JC Whisstock
Genome Res15, 537--551, 2005
Abstract