I.K. Pour, D.J. Krajnovich, et al.
SPIE Optical Materials for High Average Power Lasers 1992
We have performed ultrahigh vacuum (UHV) scanning tunneling microscopy studies of biological molecules by developing a UHV compatible cell wherein a drop of ultrapure water containing nanograms of molecules is evaporated from a strongly chemisorbing Pt(111) surface in an Ar ambient. Images are presented for hydroquinone; oligomers including pentaphenyl ether, enkephalin, and sodium dodecyl sulfate; large homopolymers of lysine and glycine; the proteins calmodulin, tropomyosin, and immunoglobin G; and double- and single-stranded plasmid DNA. In all cases the apparent height is only a few Å. Imaging properties understandably vary from clearly resolved internal molecular structure for hydroquinone to diffuse, artifact-prone images for molecules which exceed tens of angstroms in thickness. These data do not support claims for atomic resolution imaging of complex biomolecules. © 1993, American Chemical Society. All rights reserved.
I.K. Pour, D.J. Krajnovich, et al.
SPIE Optical Materials for High Average Power Lasers 1992
R.J. Gambino, N.R. Stemple, et al.
Journal of Physics and Chemistry of Solids
David B. Mitzi
Journal of Materials Chemistry
Joy Y. Cheng, Daniel P. Sanders, et al.
SPIE Advanced Lithography 2008