Sebastien joined IBM’s Computational Biology Center in the Brain Modeling and Neural Tissue Simulation Group in 2016.
He received his BSc in Computer Science from Heriot Watt University in Edinburgh, UK, MSc in Information Science from the Vrije Universiteit in Amsterdam, NL, and Ph.D. in Computational Neuroscience from Aix-Marseille Université, FR.
His PhD thesis, Multiscale Computational Modeling of Epileptic Seizure Dynamics, was conducted under supervision of Viktor Jirsa & Christophe Bernard at the Institute of Systems Neuroscience. His MSc thesis, Agent Modeling of Post-Traumatic Stress Disorders, was supervised by Jan Treur at the VU Agent Systems Group.
Sebastien now applies his previous research experience to the Computational Biology Center at IBM Research. His work within the Brain Modeling and Neural Tissue Simulation Group focuses on the validation of a computational model of cortico-striato-thalamo-cortical dynamics in the context of Huntington’s Disease.
Sebastien’s roles in the team is to integrate the outcomes of others in the group into a large-scale framework of brain activity affected by Huntington’s. He uses the Neural Tissue Simulator developped at IBM to implement the Information-Based Exchange Model introduced by James Kozloski, in the context of healthy and disease neuronal systems. The validation of a learning task against functional requirements in such framework is critical in the long-term assessment of the team’s modeling efforts.