Multiscale Modeling as a Service (MMaaS) - Selected Publications
2019
- Rizwan Ahmed, Zahra Omidian, Adebola Giwa, Benjamin Cornwell, Neha Majety, David R. Bell, Sangyun Lee, Hao Zhang, Aaron Michels, Stephen Desiderio, Scheherazade Sadegh-Nasseri, Hamid Rabb, Simon Gritsch, Mario L. Suva, Patrick Cahan, Ruhong Zhou, Chunfa Jie, Thomas Donner, and Abdel Rahim A. Hamad,
A Public BCR Present in a Unique Dual-ReceptorExpressing Lymphocyte from Type 1 Diabetes Patients Encodes a Potent T Cell Autoantigen,
Cell, 177, 1583–1599, 2019 - B Luan, G Xu, M Feng, L Cong, R Zhou,
Combined Computational–Experimental Approach to Explore the Molecular Mechanism of SaCas9 with a Broadened DNA Targeting Range,
Journal of the American Chemical Society 141 (16), 6545-6552, 2019 - Liming Wang, Peiyu Quan, Serena H. Chen, Wei Bu, Yu-Feng Li, Xiaochun Wu, Junguang Wu, Leili Zhang, Yuliang Zhao, Xiaoming Jiang, Binhua Lin, Ruhong Zhou, and Chunying Chen,
Stability of Ligands on Nanoparticles Regulating the Integrity of Biological Membranes at Nano-Lipid Interface,
ACS Nano 13, 8680-8693, 2019 - B Luan and R Zhou,
Atomic-scale fluidic diodes based on triangular nanopores in bilayer hexagonal boron nitride,
Nano letters 19 (2), 977-982,2019 - J. Christopher Octeau, Mohitkumar R. Gangwani, Sushmita L. Allam, Duy Tran, Shuhan Huang, Tuan M. Hoang-Trong, Peyman Golshani, Timothy H. Rumbell, James R. Kozloski, and Baljit S. Khakh,
Transient, consequential increases in extracellular potassium ions accompany channelrhodopsin2 excitation,
Cell Reports 27, 2249--2261, 2019 - Timothy Rumbell and James Kozloski,
Dimensions of control for subthreshold oscillations and spontaneous firing in dopamine neurons,
PLoS Computational Biology 15(9): e1007375, 2019 - Parikh J, Di Achille P, Kozloski J, Gurev V.,
Global sensitivity analysis of ventricular myocyte model-derived metrics for proarrhythmic risk assessment,
Front Pharmacol 2019;10 - Achille PD, Parikh J, Khamzin S, Solovyova O, Kozloski J, Gurev V,
Model order reduction for left ventricular mechanics via congruency training,
bioRxiv 2019 Jul 10;694075
2018 - Diego Chowell, Luc GT Morris, Claud M Grigg, Jeffrey K Weber, Robert M Samstein, Vladimir Makarov, Fengshen Kuo, Sviatoslav M Kendall, David Requena, Nadeem Riaz, Benjamin Greenbaum, James Carroll, Edward Garon, David M Hyman, Ahmet Zehir, David Solit, Michael Berger, R. H. Zhou, Naiyer A Rizvi, Timothy A Chan,
Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy,
Science, 359, 582-587, 2018 - Hongsuk Kang, Zaixing Yang, and R. H. Zhou,
Lanosterol Disrupts Aggregation of Human γD-Crystallin by Binding to the Hydrophobic Dimerization Interface,
J. Am. Chem. Soc. 140, in press, 10.1021/jacs.8b03065, 2018 - Zonglin Gu, Leigh D. Plant, Xuan-Yu Meng, Jose Manuel Perez-Aguilar, Zegao Wang, Mingdong Dong, Diomedes E. Logothetis, and R. H. Zhou,
Exploring the Nanotoxicology of MoS2: A Study on the Interaction of MoS2 Nanoflake and K+ Channels,
ACS Nano,12, 705-717, 2018 - Binquan Luan and R. H. Zhou,
Spontaneous Transport of Single-Stranded DNA through Graphene-MoS2 Heterostructure Nanopores,
ACS Nano,12, 3886-3891, 2018 - Kai Tian, Xiaowei Chen, Binquan Luan, Prashant Singh, Zhiyu Yang, Kent S Gates, Mengshi Lin, Azlin Mustapha, Li-Qun Gu,
Single Locked Nucleic Acid-Enhanced Nanopore Genetic Discrimination of Pathogenic Serotypes and Cancer Driver Mutations,
ACS Nano,12, 4194-4205, 2018 - Ge Fang, Weifeng Li, Xiaomei Shen, Jose Manuel Perez-Aguilar, Yu Chong, Xingfa Gao, Zhifang Chai, Chunying Chen, Cuicui Ge, and R. H. Zhou,
Differential Pd-Nanocrystal Facets Demonstrate Distinct Antibacterial Activity against Gram-positive and Gram-negative Bacteria,
Nature Communications, 9, 129, 2018 - Alok V. Joglekar, Zhe Liu, Jeffrey K. Weber, Yong Ouyang, John D. Jeppson, Won Jun Noh, Pedro A. Lamothe-Molina, Huabiao Chen, Seung-gu Kang, Michael T. Bethune, R. H. Zhou, Bruce D. Walker, David Baltimore,
HIV-specific T cell receptors from patients with differential immunologic control are functionally indistinguishable,
Proc. Natl. Acad. Sci., 115, 1877-1882, 2018 - Sebastien Naze, James Humble, Pengsheng Zheng, Scott Barton, Claudia Rangel-Barajas, George V. Rebec, and James R. Kozloski,
Cortico-striatal cross-frequency coupling and gamma genesis disruptions in Huntington’s Disease mouse and computational models.
eNeuro 5(6) ENEURO.0210-18.2018 - Di Achille P, Harouni A, Khamzin S, Solovyova O, Rice JJ, Gurev V,
Gaussian Process Regressions for Inverse Problems and Parameter Searches in Models of Ventricular Mechanics,
Front Physiol. 2018;9
2017 - J. Shen, B. Luan, H. Pei, Z. X. Yang, X. Zuo, G. Liu, J. Shi, L. Wang, R. H. Zhou, W. Cheng, C. H. Fan,
Humidity-Responsive Single Nanoparticle Layer Plasmonic Films,
Adv. Mater.29, 1606796, 2017 - Hongsuk Kang, Francisco X. Vázquez, Leili Zhang, Payel Das, Leticia Toledo-Sherman, Binquan Luan, Michael Levitt, and R.H. Zhou,
Emerging β-Sheet Rich Conformations in Supercompact Huntingtin Exon-1 Mutant Structures,
J. Am. Chem. Soc. 139, 8820-8827, 2017 - Lin Zhu, Daopeng Sheng, Chao Xu, Xing Dai, Mark A Silver, Jie Li, Peng Li, Yaxing Wang, Yanlong Wang, Lanhua Chen, Chengliang Xiao, Jing Chen, R. H. Zhou, Chao Zhang, Omar K Farha, Zhifang Chai, Thomas E Albrecht-Schmitt, Shuao Wang,
Identifying the Recognition Site for Selective Trapping of 99TcO4–in a Hydrolytically Stable and Radiation Resistant Cationic Metal–Organic Framework,
J. Am. Chem. Soc.139, 14873-14876, 2017 - Zonglin Gu, Lin Zhao, Shengtang Liu, Guangxin Duan, Jose M. Perez-Aguilar, Judong Luo, Weifeng Li , and R. H. Zhou,
Orientational Binding of DNA Guided by the C2N Template,
ACS Nano,11, 3198–3206, 2017 - Binquan Luan, Shuo Zhou, Deqiang Wang, R. H. Zhou,
Detecting Interactions between Nanomaterials and Cell Membranes by Synthetic Nanopores,
ACS Nano,DOI: 10.1021/acsnano.7b07005, 2017 - Rui Shi, Xing Dai, Weifeng Li, Fang Lu, Yang Liu, Huihua Qu, Hao Li, Qiongyang Chen, He Tian, Enhui Wu, Yong Wang, R. H. Zhou, Shuit-Tong Lee, Yeshayahu Lifshitz, Zhenhui Kang, Jian Liu,
Hydroxyl-Group-Dominated Graphite Dots Reshape Laser Desorption/Ionization Mass Spectrometry for Small Biomolecular Analysis and Imaging,
ACS Nano,11 9500-9513, 2017 - Zhonghe Xu, Yang Sun, Jeffrey K. Weber, Yi Cao, Wei Wang, Daniel Jasinski, Peixuan Guo, R. H. Zhou, and Jingyuan Li,
Directional mechanical stability of Bacteriophage ϕ29 motor’s 3WJ-pRNA: extraordinary robustness along portal axis,
Science Advances, 3, e1601684, 2017 - Phil De Luna, Sahar Mahshid, Jagotamoy Das, Binquan Luan, Edward H Sargent, Shana O Kelley, R. H. Zhou,
High-Curvature Nanostructuring Enhances Probe Display for Biomolecular Detection,
Nano Lett.17, 1289–1295, 2017 - Nana Luo, Jeffrey K. Weber, Shuang Wang, Binquan Luan, Hua Yue, Xiaobo Xi, Jing Du, Zaixing Yang, Wei Wei, R. H. Zhou, Guanghui Ma,
PEGylated Graphene Oxide Elicits Strong Immunological Responses Despite Surface Passivation,
Nature Communications, 8, 14537, 2017 - Zheng, Z. X. Yang, D. Gui, Z. Liu, X. Wang, X. Dai, S. Liu, L. Zhang, Y. Gao, L. Chen, D. Sheng, Y. Wang, J. Diwu, J. Wang, R. H. Zhou, Z. F. Chai, T. E. Albrecht-Schmitt, and S. Wang,
Overcoming the crystallization and designability issues in the ultrastable zirconium phosphonate framework system,
Nature Communications 8, 15369, 2017 - Li, Z. Yang, Y. Wang, Z. Bai, T. Zheng, X. Dai, S. Liu, D. Gui, W. Liu, M. Chen, L. Chen, J. Diwu, L. Zhu, R. H. Zhou, Z. Chai, T. E. Albrecht-Schmitt, and S. Wang,
A Robust Mesoporous Cationic Thorium Organic Framework that Rapidly Traps Large Anionic Persistent Organic Pollutants,
Nature Communications, 8, 1354, 2017 - Li, Z. Yang, Y. Wang, Z. Bai, T. Zheng, X. Dai, S. Liu, D. Gui, W. Liu, M. Chen, L. Chen, J. Diwu, L. Zhu, R. H. Zhou, Z. Chai, T. E. Albrecht-Schmitt, and S. Wang,
A Robust Mesoporous Cationic Thorium Organic Framework that Rapidly Traps Large Anionic Persistent Organic Pollutants,
Nature Communications, 8, 1354, 2017 - Xin Tian, Zaixing Yang, Guangxin Duan, Anqing Wu, Zonglin Gu, Leili Zhang, Chunying Chen, Zhifang Chai, Cuicui Ge, and R. H. Zhou,
Graphene Oxide Nanosheets Retard Cellular Migration via Disruption of Actin Cytoskeleton,
Small,13, 1602133, 2017 - Baoyu Li, Weifeng Li, Jose Manuel Perez-Aguilar, R. H. Zhou,
Mild Binding of Protein to C2N Monolayer Reveals Its Suitable Biocompatibility,
Small,13, 1603685, 2017 - Xiuxiu Wang, Baoyu Li, David R. Bell, Weifeng Li, R. H. Zhou,
Hydrogen and methane storage and release by MoS2 nanotubes for energy storage,
J. Mater. Chem. A 5, 23020-23027, 2017 - Parikh J, Gurev V, Rice JJ.,
Novel Two-Step Classifier for Torsades de Pointes Risk Stratification from Direct Features,
Front Pharmacol. 2017;8:816 - Trong, TM Hoang and Motley, SE and Wagner, J and Kerr, RR and Kozloski, J.
Dendritic spines modify action potential back-propagation in a multicompartment neuronal model,
IBM Journal of Research and Development 61(2/3), 11--1