Nathaniel Park  Nathaniel Park photo         

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Advanced Organic and Therapeutic Materials
Almaden Research Center, San Jose, CA, USA



Addressing Drug Resistance in Cancer with Macromolecular Chemotherapeutic Agents
Nathaniel H. Park, Wei Cheng, Fritz Lai, Chuan Yang, Paola Florez de Sessions, Balamurugan Periaswamy, Collins Wenhan Chu, Simone Bianco, Shaoqiong Liu, Shrinivas Venkataraman, Qingfeng Chen, Yi Yan Yang, James L Hedrick
J. Am. Chem. Soc., 2018


Organocatalyzed Synthesis of Fluorinated Poly(aryl thioethers).
Nathaniel H. Park, Gabriel Dos Passos Gomes, Mareva Fevre, Gavin O. Jones, Igor V. Alabugin, James L. Hedrick
Nature Communications8, 166, 2017

Convergent Approach to Boronic Acid Functionalized Polycarbonates: Accessing New Dynamic Material Platforms
Nathaniel H. Park, Zhi Xiang Voo, Yi Yan Yang, James L Hedrick
ACS Macro Letters 6(3), 252--256, ACS Publications, 2017


Palladium-and Nickel-Catalyzed Stereoselective Synthesis of Glycosyl Trichloroacetamides and Their Conversion to alpha-and beta-Urea Glycosides
Nathaniel H Park, Eric T Sletten, Matthew J McKay, and Hien M Nguyen
Domino and Intramolecular Rearrangement Reactions as Advanced Synthetic Methods in Glycoscience, pp. 297--324, Wiley Online Library, 2016

Rapid Synthesis of Aryl Fluorides in Continuous Flow through the Balz--Schiemann Reaction
Nathaniel H Park, Timothy J Senter, and Stephen L Buchwald
Angewandte Chemie 128(39), 12086--12090, Wiley Online Library, 2016

Expanding the cationic polycarbonate platform: Attachment of sulfonium moieties by postpolymerization ring opening of epoxides
Nathaniel H Park, Mareva Fevre, Zhi Xiang Voo, Robert J Ono, Yi Yan Yang, James L Hedrick
ACS Macro Letters 5(11), 1247--1252, ACS Publications, 2016


Design of New Ligands for the Palladium-Catalyzed Arylation of alpha-Branched Secondary Amines
Nathaniel H Park, Ekaterina V Vinogradova, David S Surry, and Stephen L Buchwald
Angewandte Chemie International Edition 54(28), 8259--8262, Wiley Online Library, 2015


Investigations of Scope and Mechanism of Nickel-Catalyzed Transformations o f Glycosyl Trichloroacetimidates to Glycosyl Trichloroacetamides and Subsequent, Atom-Economical, One-Step Conversionto alpha-Urea-Glycosides
Matthew J McKay, Nathaniel H Park, and Hien M Nguyen
Chemistry-A European Journal 20(28), 8691--8701, Wiley Online Library, 2014


Palladium-catalyzed synthesis of N-Aryl carbamates
Ekaterina V Vinogradova, Nathaniel H Park, Brett P Fors, and Stephen L Buchwald
Organic letters 15(6), 1394--1397, ACS Publications, 2013

Development of an air-stable nickel precatalyst for the amination of aryl chlorides, sulfamates, mesylates, and triflates
Nathaniel H Park, Georgiy Teverovskiy, and Stephen L Buchwald
Organic letters 16(1), 220--223, ACS Publications, 2013


Stereoselective Rearrangement of Trichloroacetimidates: Application to the Synthesis of alpha-Glycosyl Ureas
Nathaniel H Park, and Hien M Nguyen
Organic letters 11(11), 2433--2436, ACS Publications, 2009