Professional AssociationsProfessional Associations: International Society for Computational Biology
more informationMore information: Director of DREAM challenges | Lead of Whole cell parameter estimation | Lead of Network topology and parameter estimation | Lead of Promoter prediction | Lead of Olfaction prediction | Lead of Single cell transcriptomics | Lead of Cell lineage reconstruction
Pablo is a Research Staff member in the IBM Computational Biology Center. He joined IBM research in 2010 and received his Undergraduate degree in Physics from the University of Mexico UNAM (2000) and a Masters degree from the University of Paris VII/XI his Ph.D. in Genetics from the Rockefeller University (2005). He was awarded a Helen Hay Whitney fellowship as a posdoctoral fellow in Columbia university.
I am overall interested in applying algorithms and models to biological data and specifically how events at the molecular level determine higher order phenomena/behaviour from regulation of bacterial metabolism, mitochondrial fractional control of cell death (using our DEPICTIVE algorithm), circadian bevahiors in flies and prediction of human olfactory responses from molecular structures (see full text of recent paper in Science)
I have been lately interested in Natural Language Processing and its applications to understand descriptions of olfactory perception (see our paper Nature comms) and its applications to diagnosis of disease (see a recent NYT article on our COVID predictions through smell analysis).
I am also a director of DREAM challenges, where we look for algorithmic and Artificial Inteligence solutions in Systems Biology via crowdsourced competitions, I recently organized the Single cell transcriptomics DREAM challenge, the DREAM of Malaria challenge and the Allen institute cell lineage DREAM reconstruction challenge.
You can check my TEDx talk on DREAM challenges, "Breaking the Piñata of Science".